Glycobiology-related Enzymes
Enzymes play several crucial roles in glycobiology. For instance, transferases are involved in complex carbohydrate synthesis. In addition, carbohydrates are metabolized by glycosidases and modified by a variety of enzymes including sulfatases. As a result, these enzymes may be utilized as useful tools to understand carbohydrate structure and function. For example, they may be used to delineate or determine the structure of an oligosaccharide of interest, or modulate carbohydrate structure to see how it impacts its biological functions.
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GalNAc Transferases
- B3GALNT1
- B3GALNT2
- GM2/GD2 Synthase/ B4GALNT1
- B4GALNT2
- B4GALNT3
- B4GALNT4
- CSGalNAcT-2
- Polypeptide GalNAc Transferase 1/GALNT1
- Polypeptide GalNAc Transferase 2/GALNT2
- Polypeptide GalNAc Transferase 3/GALNT3
- Polypeptide GalNAc Transferase 4/GALNT4
- Polypeptide GalNAc Transferase 7/GALNT7
- Polypeptide GalNAc Transferase 10/GALNT10
- Polypeptide GalNAc Transferase 11/GALNT11
- Polypeptide GalNAc Transferase 12/GALNT12
- Polypeptide GalNAc Transferase 13/GALNT13
- Polypeptide GalNAc Transferase 14/GALNT14
- GALNTL1
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GlcNAc Transferases
- Alpha-1,4-N-Acetylglucosaminyltransferase 4/A4GNT
- Beta-1,3-N-Acetylglucosaminyltransferase 2/B3GNT2
- Beta-1,3-N-Acetylglucosaminyltransferase 3/B3GNT3
- Beta-1,3-N-Acetylglucosaminyltransferase 4/B3GNT4
- Beta-1,3-N-Acetylglucosaminyltransferase 6/B3GNT6
- beta-1,4-Glucuronyltransferase 1/B4GAT1
- C2GNT3/GCNT4
- EOGT
- Exostosin 1
- Exostosin 1/2 Heterodimer
- Exostosin 2
- Exostosin-like 1/EXTL1
- Exostosin-like 2/EXTL2
- Exostosin-like 3/EXTL3
- Glucosaminyl (N-acetyl) Transferase 1/GCNT1
- Glucosaminyl (N-acetyl) Transferase 2/GCNT2
- Lunatic Fringe/LFNG
- MFNG
- N-Acetylglucosaminyltransferase I/MGAT1
- N-Acetylglucosaminyltransferase 2/MGAT2
- N-Acetylglucosaminyltransferase III/MGAT3
- MGAT4A
- N-Acetylglucosaminyltransferase V/MGAT5
- Notch EGF20
- O-GlcNAc Transferase/OGT
- POMGNT1
- RFNG
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Glucosyltransferases
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Glycosidases
- alpha-Galactosidase A/GLA
- alpha-N-acetylgalactosaminidase/NAGA
- alpha-Galactosidase/a-Gal
- alpha-L-Fucosidase
- Tissue alpha-L-Fucosidase/FUCA1
- AMCase/CHIA
- beta-Galactosidase-1/GLB1
- beta-Glucuronidase/GUSB
- beta (1-3)-Galactosidase
- beta (1-4)-Galactosidase
- Chitinase 3-like 1/YKL-40
- Chitinase 3-like 2
- Chitobiase/CTBS
- Chitotriosidase/CHIT1
- Chondroitin B Lyase/Chondroitinase B
- Chondroitinase ABC
- Chondroitinase AC
- Cytosolic beta-Glucosidase/GBA3
- Endo-beta-Galactosidase
- Endo-beta-N-acetylglucosaminidase F1/Endo F1
- Endo-beta-N-acetylglucosaminidase F3/Endo F3
- Endo-beta-N-acetylglucosaminidase H/Endo H
- Endo-beta-N-acetylglucosaminidase S2/Endo S2
- Plasma alpha-L-Fucosidase/FUCA2
- Galactosylceramidase/GALC
- Glucosylceramidase/GBA
- Heparanase/HPSE
- Heparinase I
- Heparinase II
- Heparinase III
- Hexosaminidase A/HEXA
- Hexosaminidase B/HEXB
- Hyaluronan Lyase
- Hyaluronidase 1/HYAL1
- Hyaluronidase 2/HYAL2
- Hyaluronidase 4/HYAL4
- alpha-L-Iduronidase/IDUA
- Klotho
- Klotho beta
- Lactase-like Protein/LCTL
- Lysosomal alpha-Glucosidase
- MAN1A1
- MAN1A2
- MAN2A1
- MAN2B1
- MBD4
- alpha-N-acetylglucosaminidase/NAGLU
- NEU-1/Sialidase-1
- O-GlcNAcase/OGA
- O-Glycosidase
- PNGase At
- PNGase F
- SPAM1
- YM1/Chitinase 3-like 3
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Glycosyltransferase Assays and Substrates
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Neuraminidases
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Pentosyltransferases
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Sialyltransferases
- Sialyltransferase Assay Kit
- ST3 beta-Gal alpha-2,3-Sialyltransferase 1/ST3GAL1
- ST3 beta-Gal alpha-2,3-Sialyltransferase 2/ST3GAL2
- ST3GAL3
- ST3GAL4
- ST3GAL5/GM3 Synthase
- ST3GAL6
- ST6 Gal Sialyltransferase 1/ST6GAL1
- ST6 Sialyltransferase 2/ST6GALNAC2
- ST6GALNAC4
- ST6 GalNAc alpha-2,6-sialyltransferaseV/ST6GALNAC5
- ST6 Sialyltransferase 6/ST6GALNAC6
- ST6 Gal Sialyltransferase 2/ST6GAL2
- ST6 Sialyltransferase 1/ST6GALNAC1
- ST8 alpha-2,8-Sialyltransferase 8A/ST8SIA1
- ST8 alpha-2,8-Sialyltransferase 8B/ST8SIA2
- ST8 alpha-2,8-Sialyltransferase 4/ST8SIA4
- ST8 alpha-2,8-Sialyltransferase 6/ST8SIA6
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Sulfatase Modifying Factors
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Sulfotransferase Assays and Substrates
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Carbohydrate Sulfotransferases
- Carbohydrate Sulfotransferase 1/CHST1
- Carbohydrate Sulfotransferase 2/CHST2
- Carbohydrate Sulfotransferase 3/CHST3
- Carbohydrate Sulfotransferase 4/CHST4
- Carbohydrate Sulfotransferase 5/CHST5
- Carbohydrate Sulfotransferase 6/CHST6
- Carbohydrate Sulfotransferase 7/CHST7
- Carbohydrate Sulfotransferase 10/CHST10
- Carbohydrate Sulfotransferase 15/CHST15
- Galactose-3-O-sulfotransferase 2/GAL3ST2
- Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1
- Heparan Sulfate 3-O-Sulfotransferase 1/HS3ST1
- Heparan Sulfate 3-O-Sulfotransferase 4/HS3ST4
- Heparan Sulfate 6-O-Sulfotransferase 1/HS6ST1
- Heparan Sulfate 6-O-Sulfotransferase 2/HS6ST2
- Heparan Sulfate 6-O-Sulfotransferase 3/HS6ST3
- Heparan Sulfate Glucosamine 3-O-Sulfotransferase 3
- N-Deacetylase/N-Sulfotransferase 1/NDST1
- N-Deacetylase/N-Sulfotransferase 2/NDST2
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Protein Sulfotransferases
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Other Glycobiology-related Enzymes